Xeomin

What is Xeomin?

Scientifically, Xeomin is the same chemical as Botox.

Xeomin is produced and manufactured by Merz Pharmaceuticals.  It has been approved by the US Food and Drug Administration for treatment of adults with cervical dystonia or blepharospasm. The Botulinumtoxin blocks your body’s nerve activity in its muscles, which causes a temporarily reduces muscle activity.

There were 2 major clinical trials in the US, which led to the Food and Drug Administration approving it.  The Journal of Neurological Sciences did a study and deemed it “non-inferior” to Botox (equal to) while used in equal doses to treat similar symptoms. The FDA stated that Xeomin is safe and ready to use as a substitute or replacement for Botox.

100 Units of Xeomin

Both Xeomin and Botox work in the same way.  They paralyze the effected muscles and fills in wrinkle lines.  The active ingredient is the same, however Botox has an accompanying protein.

Xeomin and Botox work the same way to paralyze muscles and smooth wrinkles. They share the identical active ingredient – botulinum toxin A. The difference is that Botox has an accompanying protein, but xeomin is naked.

Dr. Grant Stevens stated, “Xeomin is another neurotoxin – it is in the same category as Botox and Dysport.  It has been used in Europe for many years.  It has less proteins then Botox, possibly making it less stable and possibly reducing the chance of resistance.  We have been using it in our office for a while and have had results consistent of Botox so far – however the cost to the consumer is cheaper with Xeomin as it stands now. ”

Xeomin has finally been approved here in the USA and offers a number of advantages to patients

• It does not have any additives
• Patients are less likely to develop a resistance
• It does not have to be kept refrigerated
• Doctors have an easy transition, being that it is used exactly the same way.
• Drugs like Xeomin will drive the cost of Botox down

Both Botox and Xeomin (as well as Dysport) are commercially made formulations of the Clostridium Botulinum bacteria.  It has been used in Europe for the past 5 years (2008-2013) mainly in Germany.  It is now being used in Europe, Asia, Canada, and the US.

Specialists say that 1 unit of Botox = 1 unit of Xeomin.  The main (claimed) advantage of Xeomin is that it claims to have removed additional proteins at higher dosages.

Many doctors are reporting that Xeomin works just as well, and they actually prefer it to Botox.

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Does Botox help for Migraines?

Botox to Treat Migraines

From Drugs.com

Botox (onabotulinumtoxinA), also called botulinum toxin type A, is made from the bacteria that causes botulism. Botulinum toxin blocks nerve activity in the muscles, causing a temporary reduction in muscle activity. It is used to prevent chronic migraine headaches in adults who have migraines for more than 15 days per month, each migraine lasting 4 hours or longer. Botox should not be used to treat a common tension headache. 

Here at Beauty Redefined we offer two brands of the Botulinum toxin A, Botox and Xeomin. For any Botulinum Toxin A treatment, effects last on average 3 months per treatment. 

Below are some reviews of patients who have gotten Botulinum Toxin A injections to treat migraines, these reviews are from drugs.com, they are not clients of Beauty Redefined. For reviews from clients of Beauty Redefined you can view them here.

Review by SXLLOVE (taken for 1 to 2 years):	User Rating:		9.0
I've been getting Botox for migraines for over a year. I used to have migraines all day, every day. This has cut them down to 2-3 times a week. Although I do have to take other medication to help with it, I'm still very grateful that my dr had me do the treatments. It's every 3 months and I end up getting 37 injections and I believe 175-200 units. The only side effect is usually a week or two after my neck will be weak and I'll have trouble holding it up if I'm bent forward to pick something up. It goes away but kind of annoying at first. I would recommend this to anyone that is a chronic migraine sufferer like myself.
December 10, 2013 6:40 PM

Review by amyzgot7boyz (taken for 6 months to 1 year):	User Rating:		10
I've had migraines for 20 years. I tried all the different preventative meds, migraine meds, including several years of narcotics. My life went to hell about two years ago when I was abruptly taken off narcotics and was not warned of opiate dependancy. So, a mother of 7 sons, not a smoker or drinker found myself in a world you only see in movies. I didn't even realize that I was addicted to pain pills, it was a normal prescription I got every month to deal with migraines. With, the help of my husband and my cousin, I was able to get off of these pills. My body was full of poison, I did it, I detoxed! I started going to a pain clinic and was introduced to Botox. It changed my life, I do get sick after shots, but it is worth it to me.
December 9, 2013 10:43 PM

Review by Marin Lady:	User Rating:		10
I had migraines for years. I tried Imitrex and similar meds but ended up with rebound headaches. It was a vicious cycle. Narcotic meds also did not work. Botox was a miracle for me. Within two weeks my migraines had disappeared entirely! The Botox lasted for 4-6 months. I changed neurologists though last month and he had a different method of injection, using twice as much Botox (200 units instead of 100). Two days later I developed horrible neck pain that progressed from sore to being barely able to hold my head up. I could not look down, bend, brush my teeth, or even turn my head. My head felt as if it weighed 200 pounds. Doctor said it would go away in 2 weeks! 10% of folks get this "side effect." I am still suffering.
May 20, 2013 3:59 AM

Review by Anxiety ridden (taken for 1 to 2 years):	User Rating:		7.0
Although this has greatly reduced my migraines in frequency and severity, the week after receiving it I go into extreme anxiety and weepiness that is crippling. It makes me nauseous and low. It subsides after about a week.
December 23, 2012 11:47 AM

Review by Anonymous (taken for 2 to 5 years):	User Rating:		10
My migraines became so severe and frequent that I was taking more abortive medications than my insurance covered. I also tried countless preventative medications but could not cope with the strange side effects of these pills. Four years ago, I started seeing a different neurologist at the military hospital and she recommended trying Botox injections. At first, I was quite hesitant. My first set of injections were practically painless. The sensation is similar to plucking eyebrow hairs, but nothing like getting a bikini wax! I've continued Botox every 3 months and my headaches are down to maybe 1 per month and they no longer affect my life as a busy mom. Botox has been a miracle for me!
September 26, 2012 11:57 PM

Review by RaeRay:	User Rating:		10
I'm very grateful the FDA approved this! I've suffered with debilitating migraines for 25 years now and have tried every medication prescribed and OTC, unfortunately the only thing that would take away the pain are narcotics. Since using Botox treatments my migraines are under control and down to approximately 4-5 a month compared to 20-25. I feel as though I have a life again and not living hour to hour, not having a life in fear of having a migraine. Also VERY grateful to have good insurance that pays for this.
December 28, 2011 3:14 AM

Review by Anonymous:	User Rating:		10
I had a constant 24/7 headache for two years straight before trying Botox. I tried every other conceivable medication to no avail, but Botox cut my pain to a third of its previous level. I still get injections every four months or so, but it's been three years and I still have the much lower pain level, can work, and am thankful everyday for Botox

Is Botox in your 20's too early?

Is Botox in your 20’s too early?

Absolutely not, as a matter a fact if someone in their 20’s begins Botulinum Treatments, the Botulinum then acts as a preventative rather than a corrective treatment. When Botulinum is injected correctly by a trained medical aesthetic professional, Botulinum will then temporarily freeze the facial muscles that cause wrinkles and frown lines. Here at Beauty Redefined we recommend that patients get treated every 3 to 6 months to keep wrinkles from coming back, and which will also prevent the facial muscles from regaining their strength and creating lines at rest. Here at Beauty Redefined we believe that the use of Botulinum at an early age will prevent those facial muscles from becoming strong enough to form those wrinkles which make us look older, more tired, and even angry. 

MedicineNet.com

Botox Information Article

Introduction

Botox is a brand name of a toxin produced by the bacterium Clostridium botulinum. There are other brand names for botulinum, such as Xeomin. In large amounts, this toxin can causebotulism, which you probably associate with food poisoning. Despite the fact that one of the most serious complications of botulism is paralysis, scientists have discovered a way to use it to human advantage. Small, diluted amounts can be directly injected into specific muscles causing controlled weakening of the muscles.

The FDA approved such usage in the late 1980s upon the discovery that Botox could stop ailments like blepharospasm (uncontrolled blinking) and strabismus (lazy eye). Doctors have been using Botox for years to successfully treat wrinkles and facial creases. In April 2002, Botox gained FDA approval for treatment of moderate-to-severe frown lines between the eyebrows - called glabellar lines. However, Botox is often used for other areas of the face as well.

How Does Botox Work?

Botox blocks signals from the nerves to the muscles. The injected muscle can no longer contract, which causes the wrinkles to relax and soften.

It is most often used on forehead lines, crow's feet (lines around the eye) and frown lines. Wrinkles caused by sun damage and gravity will not respond to Botox.

How Is a Botox Procedure Performed?

Getting Botox takes only a few minutes and no anesthesia is required. Botox is injected with a fine needle into specific muscles with only minor discomfort. It generally takes three to seven days to take full effect and it is best to avoid alcohol at least one week prior to treatment. Aspirin and anti-inflammatory medications should be stopped two weeks before treatment as well in order to reduce bruising.

How Long Does a Botox Injection Last?

The effects from Botox will last four to six months. As muscle action gradually returns, the lines and wrinkles begin to re-appear and wrinkles need to be re-treated. The lines and wrinkles often appear less severe with time because the muscles are being trained to relax.

What Are the Side Effects of Botox?

Temporary bruising is the most common side effect of Botox. Headaches, which resolve in 24-48 hours, can occur, but this is rare. A small percentage of patients may develop eyelid drooping. This usually resolves in three weeks. This usually happens when the Botox moves around so you shouldn't rub the treated area for 12 hours after injection or lay down for three to four hours.

Who Should Not Receive Botox?

Patients who are pregnant, breastfeeding or have a neurological disease should not use Botox. Since Botox doesn't work for all wrinkles, a consultation with a doctor is recommended.

Will Insurance Pay For Botox?

Insurance coverage varies for Botox injections, depending largely on the medical necessity of your condition. Botox is not generally covered by insurance when used for cosmetic purposes. Check with your insurance carrier for coverage details.

WebMD Medical Reference

SOURCE:

Merz Pharmaceuticals, LLC.

Reviewed by Michael J. Wheatley, MD on July 08, 2012